Seek and Ye Shall Find: Subclonal Anaplastic Lymphoma Kinase Mutations.
نویسنده
چکیده
Bellini and colleagues demonstrate the importance of next-generation sequencing to uncover subclonal anaplastic lymphoma kinase (ALK) mutations in neuroblastoma. Although the significance of these subclonal aberrations is not yet understood, deep sequencing could identify patients whose tumors may respond to ALK inhibitors.
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عنوان ژورنال:
- Clinical cancer research : an official journal of the American Association for Cancer Research
دوره 21 21 شماره
صفحات -
تاریخ انتشار 2015